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Similarly, sirolimus inhibits proliferation of nonimmune cells and the pathways that could be involved in oncogenesis.
Although the infiltrate in patients with CAU is characterized by more prominent granulocyte infiltrate than that of non-autoimmune patients, the frequency of other infiltrating cells is similar in both groups, although there is a slight increase in serum tryptase and cytokines in CAU patients.
In this way, polyclonal antibodies inhibit cell-mediated immune reactions, including graft rejection, (i.
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Comparison of Pharmacokinetics and Pathology for Low-Dose Tacrolimus Once-Daily and Twice-Daily in Living Kidney Transplantation.
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Pharmacokinetic evaluation of the drug interaction between intravenous itraconazole and intravenous tacrolimus or intravenous cyclosporin A in allogeneic hematopoietic stem cell transplant recipients.
Grundmann M 1 Department of Clinical Pharmacology, University Hospital and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic Aims: Psychiatric disorders such as depression and schizophrenia contribute significantly to worldwide morbidity and mortality.
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Patients receiving immunosuppressants, including Tacrolimus, are at increased risk of developing CMV viremia and CMV disease.
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Methods: Six HIV patients accepted for kidney transplantation and treated with a ritonavir-containing regimen were included.
The product tacrolimus exhibits immunosuppressive activities which are due to its effect to reduce the activity of the enzyme peptidyl-propyl isomerase and to the binding to the protein immunophilin FKBP12 (FK506 binding protein).
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